Ghrelin and cardiovascular diseases

Ghrelin and Cardiovascular Diseases

Ghrelin, a newly discovered bioactive peptide, is a natural endogenous ligand of the growth hormone (GH) secretagogue receptor and initially identified as a strong stimulant for the release of GH. Subsequent research has shown that ghrelin and its various receptors are ubiquitous in many other organs and tissues. Moreover, they participate in the regulation of appetite, energy, bodyweight, meta...

Ghrelin as a treatment for cardiovascular diseases.

G hrelin, a growth hormone–releasing peptide that was first discovered in the stomach of rats in 1999, is an endogenous ligand of growth hormone secretagogue receptors (GHSRs). 1 Through binding to its receptors in the brain, ghrelin was initially shown to strongly stimulate the release of growth hormone and promote food intake. 2 Subsequent studies revealed that GHSRs are expressed ubiquitousl...

Zooplankton and their protective effects on cardiovascular diseases

In the world-wide cardiovascular diseases are the most common. And mortallities are high. Many modifiable and non-modifiable risk factors for cardiovascular diseases have been identified. One of them is diets. In diet polyunsaturated fatty acids such omega-3 and omega-6 have protective effects on cardiovascular health. Polyunsaturated fatty acids are essentials for humans, have taken from foods...

Metabolic and Cardiovascular Effects of Ghrelin

Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is synthesized as a preprohormone and then proteolytically processed to yield a 28-amino acid peptide. This peptide was originally reported to induce growth hormone release; large evidence, however, has indicated many other physiological activities of ghrelin, including regulation of food intake and energy balance, as w...

Cardiovascular effects of ghrelin Doctoral Thesis